发明名称 |
BENZOCYCLOOCTYNE COMPOUNDS AND USES THEREOF |
摘要 |
Provided are benzocyclooctyne compounds of formula (I). These compounds undergo strain-promoted azide-alkyne cyclo additions (SPAAC) without presence of toxic metal catalysts. The provided compounds are useful for diagnosis and imaging of azide-containing molecules. Methods for detection and imaging biomolecules using compounds of the present disclosure are disclosed. |
申请公布号 |
EP2888238(A4) |
申请公布日期 |
2016.01.27 |
申请号 |
EP20130830785 |
申请日期 |
2013.08.21 |
申请人 |
ACADEMIA SINICA |
发明人 |
WONG, CHI-HUEY;FANG, JIM-MIN;SHIE, JIUN-JIE |
分类号 |
C07D311/06;A61K31/37;A61P29/00;C07D491/04;C07D493/04 |
主分类号 |
C07D311/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|