主权项 |
1. A polymer having the formula:
Y-(L1)n1-(C(O))n2—(R1)n3—R2 I wherein: Y represents: L1 represents —(CH2CH2O—)p—C(O)—C(CH3)2— or —(OCH2CH2—)p—C(O)—C(CH3)2— wherein p represents a minimum of 1 and a maximum of 20,or n1 represents 0 or 1; n2 represents 0 or 1; R1 independently represents: W independently represents —H, —CH3, —COOH, or —CH2COOH; n4a independently represents 0 or 1; n4 independently represents 0 or 1; L2 represents —NH—; R represents:
(i) C1-C12 alkyl optionally substituted with one or more hydroxyl or oxo substituents, and wherein one or more carbon atoms in the alkyl chain is optionally substituted with a heteroatom selected from the group consisting of —O—, —S—, and —NH—; (ii) phenyl or biphenyl, (iii) a carbocyclic non-aromatic ring having 5-7 carbon atoms; (iv) an aromatic heterocyclic ring having five or six atoms wherein at least one of the ring carbon atoms is substituted by a heteroatom selected from the group consisting of O, S, or NH, and (v) a non-aromatic heterocyclic ring having 5-7 carbon atoms wherein at least one of the ring carbon atoms is substituted by a heteroatom selected from the group consisting of O, S, or NH; A represents (A1)n and (A2)m; A1 represents glucose; A2 represents NIRF dye; n and m independently represent 2 to about 60; n3 represents n+m; and R2 represents H, an a straight chain or branched alkyl group having 1-6 carbon atoms, Cl or Br. |