摘要 |
New mGluR1 and mGluR5 receptor subtype preferring ligands of formula: (I) and/or salts and/or hydrates and/or solvates thereof, to the processes and intermediates for their preparation, to pharmaceutical compositions containing these compounds and to their use in therapy and/or prevention of a condition which requires modulation of mGluR1 and mGluR5 receptors.-FORMULE (I) wherein Ar1 represents an optionally substituted phenyl or heteroaryl group; Ar2 represents a substituted phenyl or an optionally substituted heteroaryl group; R1, R2, R3 and R4 represent independently a substituent selected from hydrogen, halogen, cyano, alkyl, alkoxy, hydroxy, trifluoromethyl, amino, alkylamino, dialkylamino, aminomethyl, alkylaminomethyl, dialkylaminomethyl |
申请人 |
RICHTER GEDEON NYRT. |
发明人 |
GALAMBOS, JANOS;KESERÛ, GYORGY;GÁL, KRISZTINA;BOBOK, AMRITA AGNES;WEBER, CSABA;PRAUDA, IBOLYA;WAGNER, GABOR ANDRAS;VASTAG, MONIKA |