Personal care compositions comprising self-assembling peptides

摘要

Disclosed herein are personal care compositions having at least one oligopeptide self-assembled into nanofibers or macrostructures, wherein the oligopeptide is 2-20 amino acids in length, and wherein the oligopeptide has at least one 0- to 10-amino-acid block of hydrophobic amino acids alternating with at least one 1- to 10-amino-acid block of hydrophilic amino acid residues. The composition may further include a dermatologically acceptable carrier and at least one cosmetic skin care agent.

主权项

1. A method of using a skin or hair care composition, comprising:
(a) topically applying at least one skin or hair care composition to a skin or hair surface in need of treatment, the at least one skin or hair care composition comprising a dermatologically acceptable carrier and at least one oligopeptide capable of self-assembling into nanofibers or macrostructures, wherein the oligopeptide (i) is from 2 to 20 amino acids in length, (ii) has at least one 1- to 10-amino acid block of hydrophobic amino acid residues alternating with at least one 1- to 10-amino acid block of hydrophilic amino acid residues and (iii) self assembles into nanofibers or macrostructures on the skin or hair surface; and (b) topically applying a second skin or hair care composition to the skin or hair surface, the second skin or hair care composition comprising a polymer of charge opposite to the charge of the oligopeptide of the skin or hair care composition wherein the oligopeptide and polymer of opposite charge leads to nanofibers or macrostructures on the skin or hair surface.