Devices containing dried reagents for reconstitution as calibration and/or quality control solutions, and methods of production and use thereof

摘要

Devices contain dried reagents that may be reconstituted and used in the calibration and quality control of sensors. Methods of producing and using the devices are also disclosed.

主权项

1. A device for monitoring the performance of blood gas, electrolyte and/or metabolite instrumentation, comprising:
at least one cavity having a predetermined amount of at least one lyophilized reagent disposed therein, wherein the predetermined amount of lyophilized reagent comprises at least one of a salt, a protein, and a catalyst, the at least one cavity including a first cavity; at least one activatable cavity in fluidic communication with the at least one cavity having lyophilized reagent disposed therein, the at least one activatable cavity having a predetermined amount of excipient disposed therein, wherein upon activation of the activatable cavity, the excipient moves from the at least one activatable cavity into the at least one cavity having lyophilized reagent disposed therein whereby the excipient reconstitutes the lyophilized reagent in situ to provide at least one calibration and/or quality control solution; wherein at least a portion of the device is sealed to maintain the lyophilized reagent in a substantially air tight environment until use thereof; and wherein the lyophilized reagent comprises sodium bicarbonate, the excipient comprises low pH matrix, and the reconstituted calibration and/or quality control solution comprises carbon dioxide.