发明名称 Mineral amino-acid complexes of fatty acids
摘要 The present invention relates to compound of Formula III comprising an amino acid component, a divalent metal component, and a counter-ion component, compositions containing same, and methods of use.
申请公布号 US9242008(B2) 申请公布日期 2016.01.26
申请号 US201414504247 申请日期 2014.10.01
申请人 Thetis Pharmaceuticals LLC 发明人 Sciavolino Frank C.;Mathias Gary
分类号 A61K31/42;A61K47/48;A61K31/202;A61K45/06 主分类号 A61K31/42
代理机构 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. 代理人 Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Liberto, Esq. Muriel
主权项 1. A compound of Formula III having an amino acid component, which consists of two amino acids coordinated around a divalent metal cation, a metal component, which consists of a divalent metal cation, and a counter-ion component, which consists of one or two additional molecules, A and B, ionically bound to the amino acid component, wherein R1 and R2 are the same or different and each is a side chain of an amino acid coordinated around X; X1 and X2 are H; X is selected from magnesium (Mg2+), calcium (Ca2+), or Zinc (Zn2+) as the metal component; A and B are each an omega-3 fatty acid, A and B are the same or different, and B is present or absent; and wherein B is present and A and B are independently selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA).
地址 Southport CT US