Compositions for treatment of neurodegenerative diseases

摘要

Isolated peptides are provided, being less than 20 amino acids in length. The peptides comprising an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimetics and/or fragment thereof, the peptides being capable of inhibiting alpha synuclein aggregation. Pharmaceutical compositions comprising same are also provided as well as uses thereof.

主权项

1. A peptide being less than 20 amino acids in length, the peptide comprising the amino acid sequence as set forth in SEQ ID NO: 55.