发明名称 |
Sublingual fentanyl spray |
摘要 |
The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations. |
申请公布号 |
US9241935(B2) |
申请公布日期 |
2016.01.26 |
申请号 |
US201414448752 |
申请日期 |
2014.07.31 |
申请人 |
Insys Pharma, Inc. |
发明人 |
Kottayil S. George;Goskonda Venkat R.;Zhu Zhongyuan;Kattookaran Linet;Parikh Neha |
分类号 |
A61K31/4468;A61K31/435;A61K31/445;A61K9/00;A61M11/00 |
主分类号 |
A61K31/4468 |
代理机构 |
Wood, Phillips, Katz, Clark & Mortimer |
代理人 |
Wood, Phillips, Katz, Clark & Mortimer |
主权项 |
1. A sublingual spray formulation comprising a dose of fentanyl which provides one or more mean pharmacokinetic values selected from the group consisting of: AUClast 4.863+/−1.70821 hr*ng/mL, AUCinf 5.761+/−1.916 hr*ng/milliliter, and AUCextrap 10.26+/−5.66%, when administered to humans. |
地址 |
Chandler AZ US |