发明名称 Sublingual fentanyl spray
摘要 The present invention is directed to sublingual formulations containing fentanyl, a pharmaceutically acceptable sale thereof, or derivative thereof, suitable for administration to a patient, and methods for treatment with the formulations.
申请公布号 US9241935(B2) 申请公布日期 2016.01.26
申请号 US201414448752 申请日期 2014.07.31
申请人 Insys Pharma, Inc. 发明人 Kottayil S. George;Goskonda Venkat R.;Zhu Zhongyuan;Kattookaran Linet;Parikh Neha
分类号 A61K31/4468;A61K31/435;A61K31/445;A61K9/00;A61M11/00 主分类号 A61K31/4468
代理机构 Wood, Phillips, Katz, Clark & Mortimer 代理人 Wood, Phillips, Katz, Clark & Mortimer
主权项 1. A sublingual spray formulation comprising a dose of fentanyl which provides one or more mean pharmacokinetic values selected from the group consisting of: AUClast 4.863+/−1.70821 hr*ng/mL, AUCinf 5.761+/−1.916 hr*ng/milliliter, and AUCextrap 10.26+/−5.66%, when administered to humans.
地址 Chandler AZ US