发明名称 Pharmaceutical or cosmetic composition for treating alopecia
摘要 The present invention relates to a cosmetic or pharmaceutical composition for treating alopecia, and in general for counteracting excessive hair loss, comprising as an active ingredient a compound of formula (I) R—N1-spermidine, or 1,4-butane-diamine,N-(3-aminopropyl)-N1—R. The compounds of general formula (I) are active in accordance with the objects of the present invention, and also sufficiently stable to allow effective application for topical use on the scalp without potentially being transformed into a different substance, which is no longer active, as a result of oxidation.
申请公布号 US9241888(B2) 申请公布日期 2016.01.26
申请号 US201314417598 申请日期 2013.07.26
申请人 Giuliani S.P.A. 发明人 Giuliani Giammaria;Paus Ralf;Benedusi Anna;Marzani Barbara;Baroni Sergio
分类号 A01N33/02;C07C211/00;A61K8/41;A61Q7/00;A61K31/132;C07C211/14 主分类号 A01N33/02
代理机构 LeClairRyan, a Professional Corporation 代理人 LeClairRyan, a Professional Corporation
主权项 1. A method for treating hair loss in a human subject comprising: administering one or more compounds selected from H2N—(CH2)3—N1(CH3)—(CH2)4—NH2;  (II)H2N—(CH2)3—N1(C6H11)—(CH2)4—NH2;  (III)H2N—(CH2)3—N1(C2H5)—(CH2)4—NH2;  (IV)H2N—(CH2)3—N1(C3H7)—(CH2)4—NH2;  (V)H2N—(CH2)3—N1(C4H9)—(CH2)4—NH2;  (VI)and pharmaceutically acceptable salts thereof.
地址 Milan IT