| 发明名称 | Compositions of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine | ||
| 摘要 | This invention relates to the field of pharmaceutical chemistry and, more specifically, to pharmaceutical formulations as well as to intermediates used to prepare such formulations and to methods for manufacturing such formulations. | ||
| 申请公布号 | US9241924(B2) | 申请公布日期 | 2016.01.26 |
| 申请号 | US201113165651 | 申请日期 | 2011.06.21 |
| 申请人 | CYMABAY THERAPEUTICS, INC. | 发明人 | McWherter Charles A.;Martin Robert Louis;Karpf David B.;Roberts Brian K.;Lorenz Douglas Alan;Ketner Rodney James |
| 分类号 | A61K31/506;A61P3/08;A61P3/10;A61P3/00;A61K9/10;C07D417/14;A61K31/397;A61K9/16;A61K9/20 | 主分类号 | A61K31/506 |
| 代理机构 | Foley & Lardner LLP | 代理人 | Foley & Lardner LLP |
| 主权项 | 1. A solid dispersion consisting of from about 10% to about 50% by weight of 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine free base and a water soluble, biologically compatible polymer, wherein from about 25% to about 100% by weight of the 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine is non-crystalline, and wherein the water soluble, biologically compatible polymer is cellulose acetate phthalate. | ||
| 地址 | Hayward CA US | ||