发明名称 |
A NOVEL GROUP OF STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL PATHWAY INHIBITORS |
摘要 |
The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds. |
申请公布号 |
CA2736563(C) |
申请公布日期 |
2016.01.26 |
申请号 |
CA20082736563 |
申请日期 |
2008.09.10 |
申请人 |
BOSTON BIOMEDICAL, INC. |
发明人 |
LI, CHIANG JIA;JIANG, ZHIWEI;ROGOFF, HARRY;LI, YOUZHI;LIU, JIFENG;LI, WEI |
分类号 |
C07F9/655;A61K31/665;A61P35/00;A61P35/04;C07D307/92 |
主分类号 |
C07F9/655 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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