发明名称 |
Modulatorer af glycerol-3-fosfatdehydrogenase (GPD2) til terapi |
摘要 |
Described are compounds capable of modulating (a) the biological activity of ADP-dependent glucokinase (ADPGK) and/or glycerol-3-phosphate dehydrogenase (GPD2) or (b) the expression of the gene encoding ADPGK or GPD2 for use in treating a disease (a) associated with aberrant cell proliferation, e.g., a neoplasm, or (b) of the immune system, e.g., an autoimmune disease. |
申请公布号 |
DK2532747(T3) |
申请公布日期 |
2016.01.25 |
申请号 |
DK20110004729T |
申请日期 |
2011.06.09 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM |
发明人 |
KAMINSKI, MARCIN M.;GÜLOW, KARSTEN;KRAMMER, PETER;SAUER, SVEN W. |
分类号 |
C12N15/113;A61P35/00;A61P37/00;C07K14/435 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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