发明名称 MICROBICIDALLY ACTIVE IMIDAZOPYRIDINE DERIVATIVES
摘要 The present invention provides compounds of formula (I) wherein Y1, Y2, Y3, G, V1, V2, V3 and V4 are as defined in the claims. The invention further relates to compositions which comprise these compounds and to their use in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.;
申请公布号 US2016016949(A1) 申请公布日期 2016.01.21
申请号 US201414771572 申请日期 2014.03.17
申请人 SYNGENTA PERTICIPATIONS AG 发明人 NEBEL Kurt;POULIOT Martin
分类号 C07D471/04;A01N43/90 主分类号 C07D471/04
代理机构 代理人
主权项 1. A compound of the formula (I): wherein Y1 represents hydrogen, halogen, CN, NO2, C1-C6 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C2-C6 alkenyl, C2-C6 alkynyl, phenyl, naphthyl, a 5- to 10-membered mono- or bicyclic heterocycle containing one to three heteroatoms independently selected from O, S and N, providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, wherein the heterocycle can be aromatic, or fully or partially saturated, OR1, CO2R1, COR2, CON(R3)2, N(R3)2, NR3COR2 and C(R2)═N—OR1, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, naphthyl, and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, OH, NH2, NR3COR2, SH, NO2, OR1, C1-C4 alkyl, C1-C4 haloalkyl, phenyl, halophenyl, C1-C4 alkylphenyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C1-C4 alkylthio, C1-C4 alkylsulphinyl and C1-C4 alkylsulphonyl; Y2 and Y3 are independently selected from hydrogen, halogen, CN, NO2, C1-C8 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C2-C8 alkenyl, C2-C8 alkynyl, phenyl, phenyl-C1-C6-alkyl, a 5- or 6-membered heterocycle containing one to three heteroatoms independently selected from O, S and N, providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, OR1, COR2, SH, C1-C8 alkylthio, C1-C8 alkylsulphinyl, C1-C8 alkylsulphonyl, phenylthio, phenylsulphinyl, phenylsulphonyl, N(R3)2, CO2R1, O(CO)R2, CON(R3)2, NR3COR2 and C(R2)═N—OR1, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, benzyl, and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, OH, NH2, SH, NO2, OR1, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkylthio, C1-C4 alkylsulphinyl and C1-C4 alkylsulphonyl; or Y3 is defined as above and Y1, and Y2 together with the fragment of the compound to which they are attached form a partially or fully unsaturated 5- to 7-membered carbocyclic ring or a partially or fully unsaturated 5- to 7-membered heterocyclic ring containing one to three heteroatoms independently selected from O, S, N and N(R3), providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, and wherein the ring formed by Y1 and Y2 is optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, SH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy; G represents a bond, O, S, S(O), SO2, C(O), CO2, C(R4)(R5), C(R4)(R5)—C(R6)(R7), C(R4)═C(R5), C≡C, O—C(R4)(R5), S—C(R4)(R5), C(R4)(R5)—O, C(R4)(R5)—S or phenyl; each R1 is independently selected from hydrogen, C1-C8 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkyl-C1-C2 alkyl, C3-C8 cycloalkenyl, C3-C8 alkenyl, C3-C8 alkynyl, phenyl, benzyl or a 5- or 6-membered heterocycle containing one to three heteroatoms independently selected from O, S, N and N(R3), providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, benzyl and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, OH, NH2, NO2, SH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy, C1-C4-alkoxy-C1-C4-alkyl and C1-C4 alkoxycarbonyl, and wherein the heterocycle may be attached to the rest of the molecule via a C1-C2 alkylene moeity; each R2 is independently selected from hydrogen, C1-C8 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C2-C8 alkenyl, C2-C8 alkynyl, phenyl, benzyl and pyridyl, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, benzyl and pyridyl groups are optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy, C1-C4 alkylthio and C1-C4 haloalkoxy; each R3 is independently selected from hydrogen, C1-C8 alkyl, C3-C8 alkenyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C3-C8 alkynyl, phenyl, benzyl, CN, OR1, COR2, C1-C8 alkylsulphonyl, and a 5- or 6-membered heterocycle containing one to three heteroatoms independently selected from O, S, N and N(R8), providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, benzyl and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, C1-C4 alkyl, C1-C4-haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy and C1-C4-alkoxy-C1-C4-alkyl; wherein when two radicals R3 are attached to the same nitrogen atom, these radicals can be identical or different; wherein when two radicals R3 are attached to the same nitrogen atom, both of these radicals cannot be OR1; and wherein when two radicals R3 are attached to the same nitrogen atom, these two radicals together with the nitrogen atom to which they are attached may form a cycle selected from B-1, B-2, B-3, B-4, B-5, B-6, B-7 and B-8: wherein the cycle formed is optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy; R4, R5, R6 and R7 independently of one another represent hydrogen, halogen, cyano, C1-C4 alkyl, C1-C4 alkoxy, C3-C5 cycloalkyl, C1-C4 haloalkyl, or C1-C4 alkylthio; wherein two radicals R4 and R5 or R6 and R7 or R4 and R6 together with the carbon atom to which they are attached may form a 3- to 6-membered carbocycle or heterocycle containing one to three heteroatoms independently selected from O, S, N and N(R8), providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, wherein carbocycle and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, C1-C4 alkyl, C1-C4-haloalkyl, C1-C4 alkoxy, C1-C4 haloalkoxy and C1-C4-alkoxy-C1-C4-alkyl; R8 represents hydrogen, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, C3-C8 alkenyl, C3-C8 alkynyl or C1-C8 alkoxy-C1-C8 alkyl; V1 and V2 independently of one another represent hydrogen, C1-C8 alkyl, C3-C8 alkenyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C3-C8 alkynyl, benzyl, C2-C9 alkoxycarbonyl, C4-C9 alkenyloxycarbonyl, benzyloxycarbonyl or COR2, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl and benzyl are optionally substituted by one or more groups independently selected from halogen, CN, OH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy or C1-C4 haloalkoxy; and wherein V1 and V2 together with the nitrogen atom to which they are attached may form a cycle selected from B-9, B-10, B-11, B-12 and B-13: wherein the cycle so formed is optionally substituted by one or more groups independently selected from halogen, CN, NH2, OH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy; V3 is selected from hydrogen, halogen, CN, NO2, C1-C8 alkyl, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C2-C8 alkenyl, C2-C8 alkynyl, phenyl, benzyl, a 5- or 6-membered heterocycle containing one to three heteroatoms independently selected from O, S, N and N(R3), providing that the heterocycle does not contain adjacent oxygen atoms, adjacent sulphur atoms, or adjacent sulphur and oxygen atoms, OR1, COR2, SH, C1-C8 alkylthio, C1-C8 alkylsulphinyl, C1-C8 alkylsulphonyl, phenylthio, phenylsulphinyl, phenylsulphonyl, N(R3)2, CO2R1, O(CO)R2, CON(R3)2, NR3COR2 and C(R2)═N—OR1, wherein the alkyl, cycloalkyl, cycloalkenyl, alkenyl, alkynyl, phenyl, benzyl, and heterocycle are optionally substituted by one or more groups independently selected from halogen, CN, NH2, SH, NO2, OR1, C1-C4 alkyl and C1-C4 haloalkyl; V4 is selected from hydrogen, OH, C1-C8 alkyl, C1-C8 alkoxy, C3-C8 alkenyl, C3-C8 alkenyloxy, C3-C8 cycloalkyl, C3-C8 cycloalkenyl, C3-C8 cycloalkoxy, C3-C8 alkynyl, C3-C8 alkynyloxy, phenyl, phenyl-C1-C6-alkyl, benzyloxy, pyridyl, pyridyl-C1-C6-alkyl, COR2, CO2R2, CON(R3)2 and SO2—C1-C8-alkyl, wherein the alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, phenyl, benzyl and pyridyl are optionally substituted by one or more groups independently selected from halogen, CN, NH2, NO2, OH, C1-C4 alkyl, C1-C4 haloalkyl, C1-C4 alkoxy and C1-C4 haloalkoxy; or an agriculturally acceptable tautomer, salt or N-oxide thereof.
地址 Basel CH