| 发明名称 |
TAM RECEPTORS AS VIRUS ENTRY COFACTORS |
| 摘要 |
The present invention concerns the use of an inhibitor of an interaction between phosphatidylserine and a TAM receptor for preventing or treating a virus entry cofactors, in particular phosphatidylserine harboring virus infection such as flavivirus infection. |
| 申请公布号 |
US2016015808(A1) |
申请公布日期 |
2016.01.21 |
| 申请号 |
US201314379914 |
申请日期 |
2013.02.20 |
| 申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
AMARA Ali;MEERTENS Laurent |
| 分类号 |
A61K39/395;C12N15/113;A61K31/7105;A61K38/17;A61K45/06;C07K16/28;A61K38/45 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. a method for preventing or treating a viral infection comprising administering to an individual in need thereof a therapeutically effective amount of an inhibitor of an interaction between phosphatidylserine and a TAM receptor, wherein said inhibitor is:
(i) a TAM receptor inhibitor, (ii) a Gas6 inhibitor, and/or (iii) a phosphatidylserine binding protein. |
| 地址 |
Paris FR |
