发明名称 |
BTK INHIBITORS FOR THE TREATMENT OF CNS MALIGNANCIES |
摘要 |
Described herein are irreversible BTK inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of CNS malignancies. Specifically a method of treating a CNS malignancy in a subject comprising administering to said subject, a therapeutically effective amount of a BTK inhibitor of Formula (A1) is provided, wherein the preferred CNS malignancy is glioblastoma multiforme or CNS lymphoma. |
申请公布号 |
WO2016010926(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
WO2015US40214 |
申请日期 |
2015.07.13 |
申请人 |
PHARMACYCLICS LLC |
发明人 |
SUKBUNTHERNG, JUTHAMAS;JEJURKAR, PURVI;TONEV, DANIELLE |
分类号 |
A61P35/00;A61K31/519;C07D487/04 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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