METHODS FOR TREATING HIGH CARDIOVASCULAR RISK PATIENTS WITH HYPERCHOLESTEROLEMIA
摘要
The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to a high cardiovascular risk patient a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating high cardiovascular risk patients with hypercholesterolemia and established CHD or CHD risk equivalents that are not adequately controlled by maximum tolerated dose statin therapy.
申请公布号
WO2016011260(A1)
申请公布日期
2016.01.21
申请号
WO2015US40765
申请日期
2015.07.16
申请人
SANOFI BIOTECHNOLOGY;REGENERON PHARMACEUTICALS, INC.
发明人
HANOTIN, CORINNE;BESSAC, LAURENCE;CHAUDHARI, UMESH;PORDY, ROBERT;SCHWEMMER GIPE, DANIEL, A.