HARD CAPSULE FORMULATION

摘要

A problem of the present disclosure is, in one embodiment, to create a hard capsule formulation that includes a pharmaceutical agent or the like whose components deteriorate upon contact with an acid, in which the pharmaceutical agent or the like does not deteriorate due to gastric acid penetrating into the outer shell of the hard capsule. A hard capsule formulation comprising a hard capsule with acid resistance, in which the hard capsule is not treated with enteric coating, and the hard capsule formulation comprises an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in the hard capsule.

主权项

1. A hard capsule formulation comprising:
a hard capsule with acid resistance, wherein said hard capsule is not treated with an enteric coating; and an agent to inhibit invasion of gastric fluid and a pharmaceutical agent in said hard capsule, wherein said agent to inhibit invasion of gastric fluid comprises a water repellent agent selected from the group consisting of calcium stearate, magnesium stearate, and carnauba wax.