发明名称 MEANS AND METHODS FOR IDENTIFYING A PATIENT HAVING A BRAF-POSITIVE CANCER AS A NON-RESPONDER TO A BRAF INHIBITOR AND AS A RESPONDER TO AN MAPK/ERK INHIBITOR
摘要 The present invention relates to the field of diagnostics, in particular, cancer diagnostics. More specifically, it relates to a method for identifying whether a subject suffering from a BRAF- positive cancer is a non-responder to a BRAF inhibitor, or not, and/or is a responder to an MAPK/ERK inhibitor, a method for diagnosing cancer, a method for assessing responsiveness to targeted therapy in a subject and a method for assessing cancer in a subject. Moreover, contemplated by the invention are a kit and a device for diagnosing cancer. Further, the invention relates to a MAPK/ERK inhibitor for use in treating a subject suffering from a BRAF-positive cancer.
申请公布号 WO2016008853(A1) 申请公布日期 2016.01.21
申请号 WO2015EP65986 申请日期 2015.07.13
申请人 UNIVERSITÄT ZÜRICH PROREKTORAT MNW 发明人 LEVESQUE, MITCHELL PAUL;DUMMER, REINHARD;WIDMER, DANIEL;RAAIJIMAKERS, MARIEKE INEKE GEERTJE
分类号 C12Q1/68 主分类号 C12Q1/68
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