摘要 |
An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample includes an electrically insulating base layer, an electrically conductive layer disposed on the electrically insulating base layer and including at least one electrode, an enzymatic reagent layer disposed on the at least one electrode, a patterned spacer layer, and a top layer. Moreover, the enzymatic reagent layer includes at least one naphthoquinone-based mediator and FAD-GDH enzyme. The naphthoquinone-based mediator can, for example, be at least one of, 2-naphthalenedione-4-(3-mercapto-1-propane sulfonic acid) and, 2-naphthalenedione-4-(3-mercaptopropionic acid). |