发明名称 |
ISOLATED POLYPEPTIDES OF CD44 AND USES THEREOF |
摘要 |
Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease. |
申请公布号 |
CA2951984(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
CA20152951984 |
申请日期 |
2015.07.15 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. |
发明人 |
NAOR, DAVID;ESHKAR-SEBBAN, LORA;AMAR, KEREN-OR;COHEN, SHMUEL |
分类号 |
C07K14/705;A61K38/17;A61K47/64;A61P19/02;A61P29/00;C07K1/113;C07K7/06;C07K19/00;C12N15/12;C12N15/62;C12Q1/02;G01N33/48 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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