发明名称 |
Assay Device Having Multiplexing |
摘要 |
An assay device for determining the concentration of multiple analytes or controls, where the device is capable of determining the presence or concentration of at least six analytes or controls includes: a fluid flow path; a liquid sample addition zone; a reagent zone downstream and in fluid communication with the sample addition zone containing one or more reagents; multiple detection zones in fluid communication with the reagent zone. The fluid flow path, which extends through the detection zones, has a length capable of having at least six detection zones linearly spaced at least a sufficient distance apart in order to discriminate each signal peak from its adjacent signal peak. The device further includes a wicking zone in fluid communication with the detection zones having a capacity to receive liquid sample flowing from the detection zone. The fluid flow path extends from the sample zone to the wicking zone, and at least a part of the fluid flow path has a substrate and projections which extend substantially vertically from the substrate. The projections have a height, cross-section and a distance between one another that defines a space between the projections capable of generating capillary flow parallel to the substrate surface. |
申请公布号 |
US2016018394(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
US201414333571 |
申请日期 |
2014.07.17 |
申请人 |
Ortho-Clinical Diagnostics, Inc. |
发明人 |
Danielson Susan;Kanaley James D.;Ding Zhong;Hosimer Philip C.;Hassett James W.;Warren Timothy C.;Heavner David A. |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
|
代理人 |
|
主权项 |
1. An assay device for determining the concentration of multiple analytes or controls where the device is capable of determining the presence or concentration of at least six analytes or controls comprising:
a fluid flow path;
a liquid sample addition zone;a reagent zone downstream and in fluid communication with the sample addition zone containing one or more reagents;multiple detection zones in fluid communication with the reagent zone, wherein the fluid flow path which extends through the detection zones has a length capable of having at least six detection zones linearly spaced at least a sufficient distance apart in order to discriminate each signal peak from its adjacent signal peak; and a wicking zone in fluid communication with the detection zones having a capacity to receive liquid sample flowing from the detection zone, wherein the fluid flow path extends from the sample zone to the wicking zone, and at least a part of the fluid flow path has a substrate and projections which extend substantially vertically from the substrate, wherein the projections have a height, cross-section and a distance between one another that defines a space between the projections capable of generating capillary flow parallel to the substrate surface. |
地址 |
Raritan NJ US |