发明名称 |
DELIVERY OF CARD PROTEIN AS THERAPY FOR OCCULAR INFLAMMATION |
摘要 |
The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or ocular inflammation. In an exemplary embodiment, a method is disclosed that involves administering an expression vector that delivers a secretable and cell penetrating CARD to a subject in need of treatment or prevention of age-related macular degeneration or another condition involving macular degeneration or ocular neovascularization. |
申请公布号 |
US2016017012(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
US201414775289 |
申请日期 |
2014.03.11 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
Ildefonso Cristhian J.;Lewin Alfred S.;Li Qiuhong |
分类号 |
C07K14/47;A61K9/00 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
1. A method for the prevention, amelioration, or treatment of a disease or condition associated with oxidative stress or inflammation in a subject comprising administration of a therapeutically effective amount of a agent to the subject, wherein the agent is a CARD protein. |
地址 |
Gainesville FL US |