| 摘要 |
The invention provides an autologous stem cell containing osteoinductive formulation useful for healing bone injuries and its method of preparation. The osteoinductive formulation described for healing the bone injuries is a combination of autologous mesenchymal and hematopoietic stem cells, platelet rich plasma containing mononuclear cells with growth factors and scaffolding compounds. Mesenchymal and hematopoietic stem cells used in the osteoinductive formulation are isolated from bone marrow and/or adipose tissue. Platelet rich plasma containing mononuclear cells with growth factors is isolated from peripheral blood. The invention also provides a Minimal/Non-invasive procedure for the treatment of Avascular Necrosis by administrating the osteoinductive formulation. |
