发明名称 |
NOVEL CRYSTALLINE FORM OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHENE-2-CARBOXAMIDE METHANESULFONATE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME |
摘要 |
The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism. |
申请公布号 |
CA2955397(A1) |
申请公布日期 |
2016.01.21 |
申请号 |
CA20142955397 |
申请日期 |
2014.07.18 |
申请人 |
GREEN CROSS CORPORATION;LEGOCHEM BIOSCIENCES, INC. |
发明人 |
CHOI, SOONGYU;CHOI, JUNGSUB;YOON, SO-HYUN;KIM, YOO HOON;KIM, JAE YEON;LEE, SUK HO;CHO, YOUNG LAG;SONG, HO YOUNG;LEE, DAE YON;BAEK, SUNG YOON;CHAE, SANG EUN;PARK, TAE KYO;WOO, SUNG HO;KIM, YONG ZU |
分类号 |
C07D413/14;A61K31/53;A61P9/10;A61P29/00;C07D413/10 |
主分类号 |
C07D413/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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