发明名称 NOVEL CRYSTALLINE FORM OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(5,6-DIHYDRO-4H-[1,2,4]TRIAZIN-1-YL)PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)THIOPHENE-2-CARBOXAMIDE METHANESULFONATE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
摘要 The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.
申请公布号 CA2955397(A1) 申请公布日期 2016.01.21
申请号 CA20142955397 申请日期 2014.07.18
申请人 GREEN CROSS CORPORATION;LEGOCHEM BIOSCIENCES, INC. 发明人 CHOI, SOONGYU;CHOI, JUNGSUB;YOON, SO-HYUN;KIM, YOO HOON;KIM, JAE YEON;LEE, SUK HO;CHO, YOUNG LAG;SONG, HO YOUNG;LEE, DAE YON;BAEK, SUNG YOON;CHAE, SANG EUN;PARK, TAE KYO;WOO, SUNG HO;KIM, YONG ZU
分类号 C07D413/14;A61K31/53;A61P9/10;A61P29/00;C07D413/10 主分类号 C07D413/14
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