发明名称 METHOD AND KIT FOR MAKING AN IN VITRO PROGNOSIS OF SEVERITY FOR A PATIENT IN SEPTIC SHOCK
摘要 The subject of the invention is a method for making an in vitro prognosis of severity for a patient in septic shock, including the following steps: (i) the level of expression of the expression product of at least one gene chosen from the lilrb2 and lilrb1 genes is measured in vitro on the basis of a biological sample taken from the patient, (ii) the level of expression of the expression product of the at least one gene is compared with a control level of expression, of the expression product of the same gene, with a good prognosis of severity, in which a level of expression of the expression product of the at least one gene below the control level of expression indicates a poor prognosis of severity for the patient, and also a kit for implementing the method.
申请公布号 US2016017423(A1) 申请公布日期 2016.01.21
申请号 US201414649803 申请日期 2014.01.10
申请人 BIOMÉRIEUX ;HOSPICES CIVILS DE LYON 发明人 CAZALIS Marie-Angelique;TOURNOUD Maud;VENET Fabienne;LEPAPE Alain;MONNERET Guillaume
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. Method for making an in vitro prognosis of severity for a patient in septic shock, comprising the following steps: (i) the level of expression of the expression product of at least one gene chosen from the lilrb2 and lilrb1 genes is measured in vitro on the basis of a biological sample taken from said patient, (ii) the level of expression of the expression product of said at least one gene is compared with a control level of expression, of the expression product of the same gene, with a good prognosis of severity, in which a level of expression of the expression product of said at least one gene below said control level of expression indicates a poor prognosis of severity for the patient.
地址 Marcy L'etoile FR