主权项 |
1. A method for the preparation of (2RS)-amino-(3S)-hydroxy-butyric acid or its derivative of Formula 5, comprising obtaining the compound of Formula 9 from the compound of Formula 8 by an enzymatic reduction:wherein, R1 represents hydrogen, a linear or branched C1˜C4 alkyl group, an alkylcarbonyl group, an alkoxycarbonyl group, a phenyl group, a benzyl group or a phenethyl group and wherein said alkyl can be unsubstituted or substituted with hydroxy or halogen, wherein R2 represents a linear or branched C1˜C4 alkyl group, an alkylcarbonyl group, an alkoxycarbonyl group, a phenyl group, a benzyl group or a phenethyl group, wherein said alkyl can be unsubstituted or substituted with hydroxy or halogen and wherein R1 can be the same or different than R2. |