INHIBITION OF TUMOR GROWTH WITH AGGREGATES OF SMALL MOLECULES

摘要

Disclosed herein are fibrillar molecular aggregates, which are morphologically and phenotypically similar to oligomers of aberrant proteins. The molecular aggregates, formed by self-assembly of small hydrophobic molecules, prevent the growth of microtubules. This unprecedented mechanism of “self-assembly to interfere with self-organization” allows inhibition of the growth of cancer cells.

主权项

1. A method of treating or preventing cancer, comprising the step of:
administering to a subject in need thereof a plurality of hydrophobic, self-assembling monomers.