发明名称 IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME
摘要 Provided are: a novel imidazole compound which has a high degree of stability as a compound; and a novel imidazole compound which is effective as a membrane-constituting fat of a liposome. Disclosed is a compound represented by general formula (1), and a liposome containing said compound. In the formula, Z is a substitutable imidazolyl group, L1 is a substitutable C1-4 alkylene group, X is an oxygen atom or a nitrogen-containing substituent, n is an integer from 2 to 4, m is an integer from 1 to 20, L2 is a C1-6 bivalent linking group, Y is a nitrogen-containing group, R1 and R2 are hydrogen groups or or C1-6 alkyl groups, R3 is a hydrogen atom or a substituent, and R4 and R5 are C1-40 alkyl groups.
申请公布号 WO2016010112(A1) 申请公布日期 2016.01.21
申请号 WO2015JP70399 申请日期 2015.07.16
申请人 FUJIFILM CORPORATION 发明人 OYA TOYOHISA;ISHIYAMA AYUMI;NISHIKAWA NAOYUKI
分类号 C07D233/64;A61K9/127;A61K31/713;A61K47/22;C12N15/113 主分类号 C07D233/64
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