| 发明名称 |
METHOD FOR IMPROVING HETEROLOGOUS SYNTHESIS OF ESCHERICHIA COLI INTO POLYKETIDES AND USE OF SAME |
| 摘要 |
Provided are a method for improving the heterologous synthesis of Escherichia coli into polyketides and use of same. Particularly, the present invention weakens the expression of 72 genes in host bacteria such as sucC and talB, thus dramatically improving the yield of heterologous synthesis of Escherichia coli into polyketides. |
| 申请公布号 |
WO2016008332(A1) |
申请公布日期 |
2016.01.21 |
| 申请号 |
WO2015CN79161 |
申请日期 |
2015.05.18 |
| 申请人 |
SHANGHAI INSTITUTES FOR BIOLOGICAL SCIENCES, CHINESE ACADEMY OF SCIENCES |
发明人 |
WANG, YONG;XIONG, ZHIQIANG;SONG, SHUJIE;LIU, QIAOXIA;WANG, JIANFENG |
| 分类号 |
C12N15/70;C12N1/21;C12N15/113;C12P17/08 |
主分类号 |
C12N15/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
