| 发明名称 |
METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS |
| 摘要 |
The invention relates to a method of preparing inhibitors of glucosylceramide synthase (GCS) useful for the treatment metabolic diseases, such as lysosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer. |
| 申请公布号 |
EP2970251(A1) |
申请公布日期 |
2016.01.20 |
| 申请号 |
EP20140718835 |
申请日期 |
2014.03.13 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
SIEGEL, CRAIG;GIMI, RAYOMAND;REARDON, MICHAEL;ZHAO, JIN |
| 分类号 |
C07D453/02;C07D277/30;C07D417/06 |
主分类号 |
C07D453/02 |
| 代理机构 |
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