The invention provides methods of detecting cancer and detecting activity of IDH inhibitors, and methods of screening for IDH inhibitors by detecting levels of H3K9me2.
申请公布号
EP2971079(A1)
申请公布日期
2016.01.20
申请号
EP20140710440
申请日期
2014.02.24
申请人
NOVARTIS AG
发明人
CHO, YOUNG SHIN;LEVELL, JULIAN ROY;LIN, FALLON;MCLAUGHLIN, MARGARET ELISE;MEYER, RONALD;PAGLIARINI, RAYMOND;SAENZ-VASH, VERONICA;SHEBANOVA, OLGA;ZHAI, HUILI