| 发明名称 |
インゲノール−３−アシラートＩＩＩおよびインゲノール−３−カルバメート |
| 摘要 |
The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is —NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis. |
| 申请公布号 |
JP5845283(B2) |
申请公布日期 |
2016.01.20 |
| 申请号 |
JP20130545050 |
申请日期 |
2011.12.22 |
| 申请人 |
レオ・ラボラトリーズ・リミテッドＬＥＯ ＬＡＢＯＲＡＴＯＲＩＥＳ ＬＩＭＩＴＥＤ |
发明人 |
グンナー・グルー−セレンセン;リアン・シーフー;トーマス・ヘーグベリ;クリストファー・モンソン;ペア・ヴェドセ;トーマス・ヴィフィアン |
| 分类号 |
C07D207/08;A61K8/49;A61K31/341;A61K31/343;A61K31/351;A61K31/366;A61K31/381;A61K31/40;A61K31/401;A61K31/402;A61K31/4035;A61K31/404;A61K31/415;A61K31/4155;A61K31/416;A61K31/4164;A61K31/4192;A61K31/42;A61K31/421;A61K31/423;A61K31/4245;A61K31/425;A61K31/426;A61K31/429;A61K31/437;A61K31/44;A61K31/445;A61K31/4453;A61K31/454;A61K31/47;A61K31/472;A61K31/498;A61K31/502;A61K31/505;A61K31/5375;A61K31/538;A61K31/55;A61P15/00;A61P17/02;A61P35/00;A61P35/02;A61P43/00;A61Q17/04;A61Q19/00;C07D207/16;C07D207/34;C07D209/04;C07D209/42;C07D209/44;C07D211/14;C07D211/60;C07D213/38;C07D215/06;C07D215/233;C07D215/50;C07D217/26;C07D223/14;C07D231/16;C07D231/22;C07D231/56;C07D233/90;C07D237/28;C07D239/28;C07D241/44;C07D249/06;C07D261/18;C07D261/20;C07D263/34;C07D265/36;C07D271/08;C07D275/03;C07D277/48;C07D277/56;C07D295/14;C07D307/68;C07D307/94;C07D309/38;C07D333/40;C07D405/06;C07D471/04;C07D493/08;C07D513/04 |
主分类号 |
C07D207/08 |
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