| 摘要 |
PURPOSE:To hold powder for coloring and a medical effect component in a granule and to prevent the loss of its aesthetic appreciation effect and medical effect by blending inorganic acid salt and/or organic acid salt of chitosan as a mixing agent of powder to prepare a granular agent. CONSTITUTION:Chitosan is dissolved in an aq. soln. of inorganic acid and/or organic acid and various kinds of powder becoming a constitutional component of a granular agent are added to this soln. and kneaded. Then the granular agent is produced by granulating the obtained kneaded material and drying it. The blended amount of chitosan is varied by the kind and amount of the constitutional component of the granular agent but regulated to the range of 0.5-20wt%. Inorganic acid salt or organic acid salt of chitosan is salt of deacetylated substance (chitosan) of chitin. As the powdery particle blended to the granular agent, calcium secondary phosphate, insoluble sodium metaphosphate and calcium pyrophosphate, etc., are used. |
