摘要 |
The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving 5-HT2A receptor, serotonin transporter (SERT) and/or pathways involving dopamine D2 receptor signaling systems. |
申请人 |
INTRA-CELLULAR THERAPIES, INC. |
发明人 |
LI, PENG;ZHANG, QIANG;DAVIS, ROBERT;WENNOGLE, LAWRENCE, P. |