NOVEL CYCLOPENTANE DERIVATIVES

摘要

FIELD: medicine, pharmaceutics.SUBSTANCE: claimed invention relates to compounds of formulawhere Aand R, R, R, Rand Rare determined in invention formula, which are preferable inhibitors of cathepsin cycteinprotease, in particular cathepsin S or L cycteinprotease, which makes them useful as medications, especially for treatment of diabetes, atherosclerosis, aneurism of abdominal aorta, peripheral arterial disease or diabetic nephropathy.EFFECT: invention relates to methods of obtaining claimed compounds, thereof-containing pharmaceutical composition and thereof application.24 cl, 1 tbl, 255 ex