发明名称 |
MULTIPLEXED DIGITAL ASSAY FOR VARIANT AND NORMAL FORMS OF A GENE OF INTEREST |
摘要 |
System, including methods, apparatus, and compositions, for performing a multiplexed digital assay of at least three targets. In an exemplary method, partitions may be formed each including a portion of a same sample. The sample may include a first target that is a reference sequence, a second target that is a variant sequence from a gene of interest, and a third target that is a normal sequence from the gene of interest. The target may be amplified in the partitions and amplification data may be collected. A level of the second target may be determined. A copy number of the third target may be determined from a level of the first target and a level of the third target. |
申请公布号 |
EP2971117(A2) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140762666 |
申请日期 |
2014.03.17 |
申请人 |
BIO-RAD LABORATORIES, INC.;KOEHLER, RYAN, T.;TZONEV, SVILEN, S. |
发明人 |
KOEHLER, RYAN, T.;TZONEV, SVILEN, S. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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