发明名称 |
DEAMORPHIZATION OF SPRAY-DRIED FORMULATIONS VIA SPRAY-BLENDING |
摘要 |
<p>Dry powder formulations for inhalation and their use in the treatment diseases and conditions. The formulation contains a uniform blend of a first spray-dried powder and a second spray-dried powder. The first spray-dried powder contains spray-dried particles of a therapeutically active ingredient dispersed in a pharmaceutically acceptable hydrophobic excipient. The second spray-dried powder contains spray-dried particles formed from a pharmaceutically acceptable hydrophobic excipient but are substantially free of any therapeutically active ingredient. The active ingredient in the first spray-dried powder is loaded sufficiently high to compensate for the second spray-dried powder being substantially free of any active ingredient. A process for preparing such formulations is also described.</p> |
申请公布号 |
EP2968110(A1) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140713918 |
申请日期 |
2014.03.11 |
申请人 |
NOVARTIS AG |
发明人 |
WEERS, JEFFRY;HUANG, DANIEL;TARARA, THOMAS;MILLER, DANFORTH |
分类号 |
A61K9/00;A61K9/16;A61K31/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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