| 发明名称 |
6-(HETERO-)CYCLOHEXYLALKYL SUBSTITUTED 2-QUINOLINONES/2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS |
| 摘要 |
<p>The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, s, R1, R2, R3, Q, X and Y have defined meanings.</p> |
| 申请公布号 |
EP1694653(B1) |
申请公布日期 |
2016.01.20 |
| 申请号 |
EP20040803192 |
申请日期 |
2004.11.18 |
| 申请人 |
JANSSEN PHARMACEUTICA NV |
发明人 |
MABIRE, DOMINIQUE JEAN-PIERRE;VAN DUN, JACOBUS, ALPHONSUS JOSEPHUS;SOMERS, MARIA, VICTORINA FRANCISCA;WOUTERS, WALTER BOUDEWIJN LEOPOLD |
| 分类号 |
C07D241/44;A61K31/498;A61P43/00;C07D215/22;C07D215/227;C07D401/06;C07D401/14;C07D409/14;C07D491/10 |
主分类号 |
C07D241/44 |
| 代理机构 |
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代理人 |
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