发明名称 |
SUGAR-LINKER-DRUG CONJUGATES |
摘要 |
The present disclosure relates to sugar-linker-drug conjugates, of the formula [A-B-]n-L-D, wherein A is a saccharide; B is a spacer, n is an integer selected from 1 to 3; L is a linker group and D is a drug having a chemically reactive functional group selected from the group consisting of a primary or secondary amine, hydroxyl, sulfhydryl, carboxyl, aldehyde and ketone. Pharmaceutical compositions comprising the conjugates and methods of using them are also provided. |
申请公布号 |
EP2968381(A1) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140764855 |
申请日期 |
2014.03.14 |
申请人 |
HECHT, SIDNEY;MADATHIL, MANIKANDADAS;PAUL, RAKESH;BHATTACHARYA, CHANDRABALL;TANG, CHENHONG |
发明人 |
HECHT, Sidney;PAUL, Rakesh;TANG, Chenhong;MADATHIL, Manikandadas;BHATTACHARYA, Chandraball |
分类号 |
A61K31/7042;A61K47/26;A61P35/00 |
主分类号 |
A61K31/7042 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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