发明名称 HUMAN ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS F PROTEIN AND METHODS OF USE THEREOF
摘要 The present invention provides fully human antibodies that bind to respiratory syncytial virus F protein, compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for preventing fusion of the virus with the cell membrane and preventing cell to cell spread of the virus, thereby providing a means of preventing the infection, or treating a patient suffering from the infection and ameliorating one or more symptoms or complications associated with the viral infection. The antibodies may also be useful for diagnosis of an infection by RSV.
申请公布号 EP2968534(A2) 申请公布日期 2016.01.20
申请号 EP20140714125 申请日期 2014.03.13
申请人 REGENERON PHARMACEUTICALS, INC. 发明人 GURNETT-BANDER, ANNE;PEREZ-CABALLERO, DAVID;SIVAPALASINGAM, SUMATHI;DUAN, XUNBAO;MACDONALD, DOUGLAS
分类号 A61K39/395;A61K38/16;A61K39/12;A61K39/155;A61K45/06;C07K14/00;C07K14/765;C07K16/00;C07K16/08;C07K16/10;C07K19/00;C12N15/09;G01N33/53;G01N33/566;G01N33/569 主分类号 A61K39/395
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