发明名称 |
TREATMENT FOR EXPOSURE TO NERVE AGENT |
摘要 |
The present application provides methods of preventing and treating the toxic effects of exposure to organophosphate agents. In embodiments, targeted cationic liposome complexes delivering nucleic acid molecules encoding butyrylcholinesterase and a polyproline rich peptide are administered. Suitably, the administration is via inhalation or via aerosol. Also provided are cationic liposome complexes and methods of making the complexes for such administration. |
申请公布号 |
EP2968598(A2) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140773190 |
申请日期 |
2014.03.13 |
申请人 |
GEORGETOWN UNIVERSITY |
发明人 |
CHANG, ESTHER, H.;PIROLLO, KATHLEEN, F. |
分类号 |
A61K47/48;C07K14/47;C12N9/18 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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