发明名称 |
ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER STEM CELLS |
摘要 |
The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing metastasis or relapse of a cancer in an individual previously treated for cancer with a therapy. The invention also provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating a refractory cancer (e.g., a refractory HPV-associated cancer). |
申请公布号 |
EP2970970(A1) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140770117 |
申请日期 |
2014.03.14 |
申请人 |
ANDES BIOTECHNOLOGIES S.A. |
发明人 |
BURZIO ERIZ, LUIS, O.;BURZIO MENENDEZ, VERONICA A.;VILLEGAS OLAVARRIA, JAIME E. |
分类号 |
C12N15/11;A61K48/00;C12N5/00;C12N15/00 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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