发明名称 |
TRANSDERMAL DELIVERY OF SILDENAFIL AND OTHER PHOSPHODIESTERASE TYPE 5 INHIBITORS |
摘要 |
The present invention generally relates to the transdermal delivery of sildenafil and other phosphodiesterase type 5 inhibitors. While transdermal transport of sildenafil in creams and other topical formulations have been previously described, propylene glycol has not previously been recognized as a transdermal enhancer. However, in some aspects of the present invention, certain concentrations of propylene glycol can have a surprising effect on the transdermal delivery of sildenafil and other phosphodiesterase type 5 inhibitors, e.g., doubling the amount of transdermal delivery in some cases. |
申请公布号 |
EP2968130(A1) |
申请公布日期 |
2016.01.20 |
申请号 |
EP20140721633 |
申请日期 |
2014.03.14 |
申请人 |
STRATEGIC SCIENCE & TECHNOLOGIES, LLC |
发明人 |
FOSSEL, ERIC, T.;GUTMAN, LORIN |
分类号 |
A61K9/06;A61K9/107;A61K31/519;A61K47/02;A61K47/10;A61K47/12;A61K47/18 |
主分类号 |
A61K9/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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