发明名称 [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-[7-FLUORO-1-(2-METHOXY-ETHYL)-4TRIFLUOROMETHOXY-1H-INDOL-3-YL]METHANONE AS AN INHIBITOR OF MAST CELL TRYPTASE
摘要 The present invention is directed to an indole benzylamine compound of formula I: useful as an inhibitor of tryptase. In addition, the present invention is directed to the use of the compound for treating a patient suffering from, or subject to, a physiological condition in need of amelioration by inhibition of tryptase, comprising administering to the patient of a therapeutically effective amount of the compound, and to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier.
申请公布号 PT2367812(E) 申请公布日期 2016.01.20
申请号 PT20090791693T 申请日期 2009.08.20
申请人 SANOFI;SANOFI 发明人 YONG-MI CHOI-SLEDESKI;NAKYEN CHOY;GREGORY BERNARD POLI;JOHN J. SHAY JR.;PATRICK WAI-KWOK SHUM;ADAM W. SLEDESKI
分类号 C07D401/06;A61K31/404;A61P29/00 主分类号 C07D401/06
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