The present disclosure is directed toward composite materials comprising high aspect ratio habits of drug crystals which can be partially or fully extending into a substrate, and additionally, can be projecting from a substrate at an angle of about 20° to about 90°. The present disclosure is directed toward medical devices, such as medical balloons, comprising said composite and methods of using and making the same. The described composite can be used for the local treatment of vascular disease. The present disclosure is also directed toward paclitaxel crystals with a hollow acicular habit.
申请公布号
EP2968252(A1)
申请公布日期
2016.01.20
申请号
EP20140717612
申请日期
2014.03.14
申请人
W. L. GORE & ASSOCIATES, INC.
发明人
CLEEK, ROBERT, L.;CULLY, EDWARD, H.;DRUMHELLER, PAUL, D.;LI, MEI;TRAYLOR, PETER, D.