发明名称 |
Methods for treatment of pain |
摘要 |
The invention provides for methods and compositions for treatment of pain via craniofacial mucosal administration of an analgesic compound (e.g. a non-opioid analgesic peptide, an NOP agonist or N/OFQ). Intranasal administration of certain analgesic peptides such as N/OFQ results in global analgesic effects. |
申请公布号 |
US9238053(B2) |
申请公布日期 |
2016.01.19 |
申请号 |
US201313802075 |
申请日期 |
2013.03.13 |
申请人 |
Nocicepta LLC |
发明人 |
Toll Lawrence R.;Yeomans David C.;Angst Martin S.;Jacobs Daniel I. |
分类号 |
A61K38/10;A61K38/00;C07K7/08;C07K7/00;A61K9/00;A61K31/485;A61K38/08;A61K45/06 |
主分类号 |
A61K38/10 |
代理机构 |
Morrison & Foerster LLP |
代理人 |
Morrison & Foerster LLP |
主权项 |
1. A method for the treatment of pain comprising administering to an individual in need thereof an effective dose of a non-opioid peptide NOP agonist via intranasal administration, provided when the pain is a trigeminal nerve-associated pain, the non-opioid peptide NOP agonist is not co-administered with an oxytocin peptide. |
地址 |
Wilmington DE US |