发明名称 |
Phenyl amino pyrimidine compounds and uses thereof |
摘要 |
The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases. |
申请公布号 |
US9238628(B2) |
申请公布日期 |
2016.01.19 |
申请号 |
US201313913362 |
申请日期 |
2013.06.07 |
申请人 |
YM Biosicences Australia PTY LTD |
发明人 |
Burns Christopher John;Donohue Andrew;Feutrill John Thomas;Nguyen Thao Lien Thi;Wilks Andrew Frederick;Zeng Jun |
分类号 |
C07D413/00;A61K31/535;C07D239/42;C07D295/02;C07D295/12;C07D401/12;C07D403/12;C07D405/12;C07D417/12;C07D401/14 |
主分类号 |
C07D413/00 |
代理机构 |
|
代理人 |
Dammann Yu-Ming |
主权项 |
1. A compound having the structure of:or a pharmaceutically acceptable salt thereof. |
地址 |
Foster City CA US |