[3-HETEROARYL-2-TRIFLUOROMETHYL-PROPYL]-PIPERIDIN-1-YLE OR - MORPHOLIN-4-YLE COMPOUNDS AS TRPA1 ANTAGONISTS FOR THE TREATMENT OF RESPIRATORY DISEASES TRPA1 [3--2--]- -1---4-

摘要

The invention is concerned with the compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists of the TRPA1 channel and may be useful in treating inflammatory diseases and disorders associated with that channel.