WATER-INSOLUBLE RUTHENIUM CATALYST COMPOSITION FOR USE IN AQUEOUS HYDROGENATION REACTIONS

摘要

The invention relates to a method for converting a precatalyst complex to an active catalyst complex, wherein the precatalyst complex and the active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, and the active catalyst complex furthermore comprises a monohydride and a water molecule. The method comprises the steps of providing water as an activation solvent system with a pH value equal or below 2, and solving said precatalyst complex, an acid, and hydrogen therein. The invention further relates to a method for manufacturing a catalyst composition, a method for hydrogenating a substrate molecule and a reaction mixture.

主权项

1. A method for converting a precatalyst complex to an active catalyst complex,
wherein said precatalyst complex and said active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, and wherein said active catalyst complex comprises a monohydride and a water molecule, said method comprising the steps of: a) providing an activation solvent system comprising water, b) adding to, particularly solving in, said activation solvent system
said precatalyst complex,a solubilizer,an acid, andhydrogen, characterized in that the pH value of said activation solvent system is equal or below 2 after addition of said acid.