MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide aryl- and heteroaryl-fused decahydropyrroloazepine, octahydrooxepinopyrrole, octahydropyrrolothiazepine dioxide, decahydrocyclohepta[c]pyrrole, and octahydrocyclohepta[c]pyrrole derivatives, and pharmaceutical compositions comprising such compounds.SOLUTION: The present invention relates to compounds represented by formula (I), and pharmaceutical compositions comprising these compounds effective in treatment of disease of the nervous system or the like. [Rto Rare each independently H, alkyl, or the like; Yto Ytogether with the neighboring carbon atoms form a nitrogen-containing heterocycle or the like; and A is a sulfur-containing heterocycle or the like.]